国家卫生研究院:银屑病保健品综述

银屑病 (psoriasis) 俗称牛皮癣,一种慢性炎症皮肤病,病程长,易复发,几乎终生不愈。发病以青壮年为主,临床表现为红斑、鳞屑,全身均可发病,以头皮,四肢伸侧更常见,冬季加重。

以下整理自国家卫生研究院关于银屑病保健品的综述文章。有证据表明,鱼油、死海气候疗法和外用药草俄勒冈葡萄提取物和靛蓝可能对银屑病治疗有益。 [来源]

鱼油 / Fish oil

  • 2015 年的一项评论指出,有多个证据表明鱼油 (fish oil) 对银屑病治疗有效。
  • 维生素 D 、维生素 B12 和硒 (selenium) 治疗银屑病的研究不能得出一致结论。
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外用维生素 D 软膏

2013 年,国际权威的循证医学学术组织 Cochrane 在对 177 项相关研究 (共 34,808 名参与者) 的回顾中发现,

  • 维生素 D 软膏的效果好于安慰剂,它的作用与外用皮质类固醇 (topical corticosteroids) 相似;
  • 然而,对于头皮牛皮癣,外用皮质类固醇的效果好于维生素 D 软膏;
  • 维生素 D 配合皮质类固醇的效果,好于单独用维生素 D 或皮质类固醇。

外用维生素 D 软膏可能引起不适,如刺激皮肤和灼烧感等。

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NIH:儿童和成人所需的钙摄入量

气候疗法 / Climatotherapy

利用有利的自然气候条件 (如气候、海水、阳光等资源) 使身体康复的一种疗法。

  • 对照试验表明,死海气候疗法 (Dead Sea climatotherapy) 可以改善银屑病,治疗效果明显。研究发现,死海海水里含有的一些成分对治疗皮肤炎症有辅助疗效。死海的海水盐分是普通海水盐分的 10 倍,而且含有钾、镁等矿物质和大量的微量元素,加上死海地区阳光充足,又低于海平面几百米,阳光中对人体的有害光线更少、治疗的光线更多,为死海治疗皮肤病提供了独一无二的优越条件。然而,紫外线暴露可能增加黑色素瘤和非黑色素瘤皮肤癌的风险,应仔细权衡气候疗法的益处与患者风险。
  • 在死海以外地区应用气候疗法的研究尚缺乏相关证据。

光疗 / Light Therapy

即利用光线的辐射能治疗疾病的理疗法。

  • 2015 年,一项针对 21 名斑块状银屑病患者的随机对照试验结果表明,光疗可激活口服姜黄提取物 (curcuma longa) 在治疗中重度银屑病时的治疗反应。
  • 2015 年,在对 47 例轻度寻常型银屑病患者进行的一项随机对照试验中,科学家评估了长期接受无紫外线蓝光治疗 (long-term UV-free blue light treatment) 的安全性和有效性,与对照组相比,蓝光治疗可显著改善患者银屑病病症。
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各种皮肤问题啊!

中药

  • 有证据表明,口服中药 (Traditional Chinese medicine) 与常规治疗相结合的疗法比单独使用常规治疗更有效。

草本外用保健品

  • 2015 年,银屑病治疗辅助方法中指出,俄勒冈葡萄提取物 (mahonia aquifolium,Oregon grape) 和天然靛蓝 (Indigo naturalis) 提取物对银屑病治疗有效。较少证据表明芦荟 (aloe vera) 、印度楝树 (neem) 和甜性乳清提取物在银屑病治疗中有效果。
  • 2013 年,对银屑病治疗应用的植物提取物进行系统综述和分析得出结论,相对于安慰剂组,俄勒冈葡萄提取物和天然靛蓝提取物在斑块状银屑病中发挥有限效果; 但尚无法评估其影响程度和效果持续时间。

然而,一些中草药被发现重金属或皮质类固醇污染。其他安全问题包括中草药补充剂引起的中毒或接触性皮炎等。需要谨慎使用。

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