美国大约十分之一的成年人患有抑郁症。抑郁症可以用传统药物治疗，包括抗抑郁药物和心理治疗。更多关于抑郁症的信息，点此查看。许多抑郁症患者在常规治疗之外还会尝试替代医学，但这些治疗方法目前还没有深入的研究。美国国家卫生研究院（NIH）对此提出了5点建议，原文在此。
Omega-3 脂肪酸补充剂
一些研究表明，Omega-3脂肪酸补充剂与传统的治疗方法（如抗抑郁药物）结合时，对患有重度抑郁症（MDD）的患者、以及没有诊断出 MDD 的抑郁病患的病情可能有稍许改善。但是，关于 Omega-3 补充剂如何（或能否）真正起作用，仍存在许多疑问。
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St. John's Wort 贯叶连翘
一些关于贯叶连翘的研究发现，在有限数量的患者身上，它的疗效与标准抗抑郁药相似；但另外一些研究则并未有类似的发现。此外，有研究发现，贯叶连翘会与许多药产生反应，影响这些药物的效果，因此其风险可能比益处更大。
有折扣
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膳食补充剂
目前没有科学研究证明包括 S-腺苷甲硫氨酸（SAMe）和肌醇（inositol）等膳食补充剂有治疗抑郁症的功效。
身心调整
注重身心健康方面的调理，可以帮助对抗抑郁症。例如，目前已经有一些研究表明音乐疗法可以改善情绪。此外，也有研究表明做一些放松训练有助于缓解抑郁症症状，但它的效果不如认知行为疗法等心理疗法。
和医生沟通
尝试任何替代医学疗法前，应当及时、主动和你的医生沟通，共同商讨最适合你的治疗方案。
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