卡耐基梅隆大学是美国著名的私立高校，每年招收数千名国际学生（2017 年 statictics 参见这里）。它的「Swartz 创业中心」「Swartz Center for Entrepreneurship」 致力于帮助该校学生、员工和校友创业，并在卡耐基梅隆大学官网发表了一系列问答：Starting a Business While in F-1 Student Status；原文参见这里。下面是我的编译／解读。
Q. I’m in F-1 status. Can I work in the US? A. Yes, you are eligible to work part-time for Carnegie Mellon University while school is in session and full-time (for Carnegie Mellon) during your vacation periods.
Q. Can I work off campus? A. To work off campus or for an employer other than Carnegie Mellon, you must have some type of employment authorization. The most common types of off campus employment authorization for F-1 students are Curricular Practical Training (CPT) and Optional Practical Training (OPT).
解读：F-1 若为其他雇主工作必须有工作许可，最常见的是 CPT／OPT 。
Q. Can I invest in the market or in a business? A. Yes, but profits will be taxable and there may be immigration implications if it’s your business.
Q. Can I start a business while I’m in F-1 status? A. Maybe—in terms of immigration rules, guidance from the Student and Exchange Visitor Program (SEVP) has been that starting a business is likely to constitute employment and an F-1 student would therefore need to have employment authorization in order to maintain F-1 status. Government guidance is that OPT would be the appropriate employment authorization for starting a business.
解读：创业可能被视为「工作」，F-1 创业必须要有工作许可，比如 OPT 。
Q. What if I volunteer—is that legal for F-1 students? A. While Immigration regulations allow F-1 students to volunteer, labor regulations do not allow employers to have 「volunteers」 performing work they would normally hire someone to perform. We do not recommend that F-1 students 「volunteer」 for professional positions as the employer may be obligated to provide compensation for the services rendered and pay the student for the 「volunteer」 work. If an F-1 student doesn’t have employment authorizationand the employer pays them for the 「volunteer」 work, the student may end up working without authorization. The US Dept. of Labor is increasingly interested in monitoring employers who may be improperly using volunteers. Additionally, students often like to note 「volunteer」 opportunities on resumes which may give the impression that the experience was 「employment」 for which the individual should have had employment authorization. Students, and employers, need to be careful about 「volunteer」 experiences to make sure there are no violations of any applicable regulations.
Q. If starting a business is likely to constitute employment, what employment authorization should I have?A. For students in F-1 status, the US Dept. of Homeland Security indicates: 「The U.S. government considers starting your own business in the United States, also known as entrepreneurship, as work. Therefore, if you are an F-1 student who plans to start your own business in the United States, you must qualify and apply for OPT. Employment on OPT must be directly related to your major field of study. Information about other immigration options may be found at: https://www.uscis.gov/eir/visaguide/entrepreneur-visa-guide#Nonimmigrant
解读：F-1 创业需要申请 OPT，必须与你所学专业有关。
Q: Is there anything that I can do toward starting my business while still on an F-1 visa that doesn’t violate my student status or specifically require employment authorization? A: Yes. You can engage in discussions or conduct research such as performing customer discovery, engaging in competitive Analysis, exploring potential company formation options and equity arrangements with cofounders, building a test model to explore the technical feasibility of a product, drafting potential marketing materials, etc.
Q. Can I use OPT during my program? A. Yes, OPT can be used part-time while school is in session or full-time during vacation periods or full-time after all requirements for the degree, excluding the thesis or dissertation, are complete.
解读：尚未毕业也可使用 OPT 工作，但有些限制条件。
Q. OPT is only for 12 months per level of study. What do I do after that? A. If you pursue a higher level of study, you would be eligible for another 12-month period of OPT (which could be used part-time while school is in session). Alternatively, if you are in your post-completion period of OPT, if you were in a designated STEM field and if your company fully participates in E-Verify, you are eligible to apply for a 24- month STEM OPT extension. If you don’t qualify for the STEM OPT extension, you would need to change to another immigration status. One possible option is to have your employer/company file for H-1B status on your behalf. NOTE: SEVP guidance is that 「F-1 students cannot qualify for STEM OPT extensions unless they will be bona fide employees of the employer signing the Form I-983 because F-1 students may not provide employer attestations on their own behalf.」 The STEM OPT cannot, therefore, be used if you are the sole proprieter of the company as you cannot be your own employer.
Q. Are there other options for employment authorization besides OPT? A. If the company is financially viable, it may be able to sponsor you for H-1B status. Alternatively, the International Entrepreneur Rule that will become effective July 17, 2017. This rule provides employment authorization for eligible entrepreneurs who have established a start-up and who meets the specified criteria. NOTE: US immigration regulations, policies and procedures are subject to change. As you make your plans, pay attention to the current regulatory/policy environment.
波士顿的律师事务所 The Jacobs Law LLC 在官网发表了一篇文章，Can I Start a Business While in the U.S. on a Student Visa? 原文在这里。我引用摘要如下：
In general, international students in F1 status are forbidden from 「engaging in business.」 However, immigration law does not expressly forbid F1 visa students from establishing their own business because ‘preliminary business planning’ is not considered ‘engagement’. Once the business is established, however, International Students are not permitted to operate their own business, engage in business, or receive revenue, compensation or salary.[…]
Often International Students will ask whether they can ‘run’ their own business without receiving any compensation, revenue or salary. But consider this – Working for a for-profit company without receiving pay cannot be considered volunteering, and is therefore forbidden for F1 visa holders.
Through investments, International students can receive benefits from their company, without engaging in business. Immigration law allows International Students to invest in their own company and receive dividends.[…] However, an F1 visa student still cannot engage in business without obtaining additional visa status.